Yes, dosage plays a critical role in the intensity and speed of appetite suppression
However, certain medical conditions require specific precautions
Alcohol Alcohol irritates the stomach lining, and because semaglutide prolongs gastric residence time, drinks tend to hang around longer and increase nausea and reflux
For people with high blood pressure, this can be an encouraging added benefit
Have bland backup foods available in case nausea hits
Appropriate reasons to discuss discontinuation include achieving your weight loss goals and wanting to attempt weight maintenance without medication, experiencing intolerable side effects that don't improve with dose adjustment or supportive management, financial constraints that make continued treatment unsustainable, planning pregnancy (semaglutide is not recommended during pregnancy and should be discontinued at least two months before conception), or developing contraindications to continued use